Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPC5 | Q9UL62 | 4/20 | 0.46 |
| ▸ | TRPC4 | Q9UBN4 | 2/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.46 |
| ▸ | TRPC1 | P48995 | 1/20 | 0.42 |
| ▸ | BRAF | P15056 | 2/20 | 0.41 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.41 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | DPP4 | P27487 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.37 |
| ▸ | PCSK9 | Q8NBP7 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9707689 | 0.92 | TRPC5 (0.45) | TRPC5TRPC4KCNH2TRPC1BRAF | |
| SCHEMBL9708321 | 0.89 | ALDH1A1 (0.44) | TRPC5TRPC4KCNH2TRPC1BRAF | |
| SCHEMBL9707666 | 0.88 | ADORA3 (0.42) | ADORA3 | |
| SCHEMBL9708923 | 0.86 | TRPC4 (0.47) | TRPC5TRPC4KCNH2TRPC1 | |
| SCHEMBL9708027 | 0.85 | MAPT (0.42) | ADORA3LMNATSHRNPSR1ALDH1A1 | |
| SCHEMBL9708532 | 0.84 | TRPC4 (0.46) | TRPC5TRPC4KCNH2TRPC1NPSR1 | |
| SCHEMBL9707874 | 0.83 | TRPC4 (0.43) | TRPC5TRPC4KCNH2TRPC1BRAF | |
| SCHEMBL9707771 | 0.81 | ALDH1A1 (0.45) | TRPC5TRPC4KCNH2TRPC1BRAF | |
| SCHEMBL9707888 | 0.81 | ADORA3 (0.41) | ADORA3 | |
| SCHEMBL9707876 | 0.80 | GPR18 (0.38) | KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992007852-A1 | BIPHENYLALKYL XANTHINE COMPOUNDS FOR TREATMENT OF CARDIOVASCULAR DISORDERS | G.D. SEARLE & CO. (US) | 1992-05-14 | — | — | WO | disclosed |