Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | USP1 | O94782 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9707857 | 0.94 | ALDH1A1 (0.38) | ALDH1A1POLBUSP1MAPTSMN1; SMN2 | |
| SCHEMBL9707862 | 0.93 | PPARG (0.37) | USP1 | |
| SCHEMBL9707505 | 0.91 | ADORA3 (0.40) | — | |
| SCHEMBL9707740 | 0.91 | PPARG (0.35) | — | |
| SCHEMBL9708111 | 0.91 | ALDH1A1 (0.39) | ALDH1A1POLBMAPTHPGDSMN1; SMN2 | |
| SCHEMBL9707977 | 0.91 | ALDH1A1 (0.44) | ALDH1A1POLBMAPTSMN1; SMN2HIF1A | |
| SCHEMBL9707896 | 0.90 | DPP4 (0.37) | ALDH1A1USP1MAPTHPGDSMN1; SMN2 | |
| SCHEMBL9708894 | 0.90 | AGTR1 (0.35) | USP1 | |
| SCHEMBL9707440 | 0.89 | AGTR1 (0.41) | ALDH1A1POLBSMN1; SMN2ALOX15HSD17B10 | |
| SCHEMBL9708014 | 0.89 | AGTR1 (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992007852-A1 | BIPHENYLALKYL XANTHINE COMPOUNDS FOR TREATMENT OF CARDIOVASCULAR DISORDERS | G.D. SEARLE & CO. (US) | 1992-05-14 | — | — | WO | disclosed |