Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | TSHR | P16473 | 4/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | PCSK9 | Q8NBP7 | 1/20 | 0.43 |
| ▸ | DPP4 | P27487 | 1/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9708010 | 0.92 | MAPT (0.41) | MAPTPOLBDPP4MEN1KMT2A | |
| SCHEMBL9708826 | 0.92 | HPGD (0.41) | ATM | |
| SCHEMBL9707347 | 0.91 | RAB9A (0.44) | SMN1; SMN2HSD17B10LMNAMAPTTSHR | |
| SCHEMBL9708648 | 0.91 | ADORA1 (0.42) | MAPTDPP4 | |
| SCHEMBL9708391 | 0.91 | PDE1A (0.44) | SMN1; SMN2LMNATSHRNPSR1 | |
| SCHEMBL9707814 | 0.91 | ADORA3 (0.42) | SMN1; SMN2LMNA | |
| SCHEMBL9708044 | 0.91 | ALDH1A1 (0.38) | ALDH1A1SMN1; SMN2HIF1AALOX15HSD17B10 | |
| SCHEMBL9707660 | 0.91 | USP1 (0.39) | ALDH1A1SMN1; SMN2ALOX15HSD17B10LMNA | |
| SCHEMBL9708188 | 0.91 | USP1 (0.39) | ALDH1A1SMN1; SMN2ALOX15HSD17B10LMNA | |
| SCHEMBL9707902 | 0.90 | HPGD (0.43) | ALDH1A1SMN1; SMN2ALOX15HSD17B10LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992007852-A1 | BIPHENYLALKYL XANTHINE COMPOUNDS FOR TREATMENT OF CARDIOVASCULAR DISORDERS | G.D. SEARLE & CO. (US) | 1992-05-14 | — | — | WO | disclosed |