Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | ADORA1 | P30542 | 5/20 | 0.40 |
| ▸ | ADORA3 | P0DMS8 | 4/20 | 0.40 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.40 |
| ▸ | ADORA2B | P29275 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | CASP1 | P29466 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | CASP7 | P55210 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | BRAF | P15056 | 1/20 | 0.37 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9707347 | 0.91 | RAB9A (0.44) | RAB9AMEN1KMT2AADORA1ADORA3 | |
| SCHEMBL9708591 | 0.91 | ADORA1 (0.40) | ADORA1ADORA3ADORA2AADORA2BMAPK1 | |
| SCHEMBL9708262 | 0.87 | HPGD (0.42) | MEN1KMT2ALMNANPSR1MAPK1 | |
| SCHEMBL9708010 | 0.85 | MAPT (0.41) | RAB9AMEN1KMT2AADORA1ADORA3 | |
| SCHEMBL9707680 | 0.85 | ADORA3 (0.43) | MEN1KMT2AADORA1ADORA3ADORA2A | |
| SCHEMBL9708391 | 0.85 | PDE1A (0.44) | LMNANPSR1SMN1; SMN2CASP1TSHR | |
| SCHEMBL9708251 | 0.84 | ALDH1A1 (0.37) | MEN1KMT2ALMNANPSR1SMN1; SMN2 | |
| SCHEMBL9708819 | 0.84 | ADORA3 (0.44) | ADORA1ADORA3ADORA2AADORA2B | |
| SCHEMBL9708697 | 0.84 | ADORA3 (0.39) | MEN1KMT2AADORA1ADORA3ADORA2A | |
| SCHEMBL9708654 | 0.83 | ADORA3 (0.42) | ADORA1ADORA3ADORA2AADORA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992007852-A1 | BIPHENYLALKYL XANTHINE COMPOUNDS FOR TREATMENT OF CARDIOVASCULAR DISORDERS | G.D. SEARLE & CO. (US) | 1992-05-14 | — | — | WO | disclosed |