Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | USP1 | O94782 | 3/20 | 0.40 |
| ▸ | DPP4 | P27487 | 1/20 | 0.40 |
| ▸ | BRAF | P15056 | 1/20 | 0.39 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.39 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.38 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.38 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.38 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9708648 | 0.94 | ADORA1 (0.42) | MAPTRAB9AUSP1DPP4BRAF | |
| SCHEMBL9708826 | 0.93 | HPGD (0.41) | USP1 | |
| SCHEMBL9708350 | 0.92 | ADORA3 (0.43) | ADORA3ADORA2AADORA2BADORA1 | |
| SCHEMBL9707347 | 0.92 | RAB9A (0.44) | MAPTRAB9AUSP1DPP4BRAF | |
| SCHEMBL9707977 | 0.92 | ALDH1A1 (0.44) | MAPTDPP4MEN1POLBKMT2A | |
| SCHEMBL9708609 | 0.91 | POLB (0.44) | MAPTRAB9ABRAFPIK3CGADORA3 | |
| SCHEMBL9707864 | 0.90 | DCTPP1 (0.46) | RAB9AUSP1DPP4MEN1KMT2A | |
| SCHEMBL9707843 | 0.90 | ADORA1 (0.42) | MAPTADORA3ADORA2AADORA2BADORA1 | |
| SCHEMBL9708431 | 0.90 | ADORA1 (0.40) | ADORA3ADORA2AADORA2BADORA1 | |
| SCHEMBL9708215 | 0.90 | ADORA3 (0.42) | MAPTRAB9AUSP1DPP4BRAF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992007852-A1 | BIPHENYLALKYL XANTHINE COMPOUNDS FOR TREATMENT OF CARDIOVASCULAR DISORDERS | G.D. SEARLE & CO. (US) | 1992-05-14 | — | — | WO | disclosed |