Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR2 | P50052 | 10/20 | 0.53 |
| ▸ | AGTR1 | P30556 | 9/20 | 0.53 |
| ▸ | PPARG | P37231 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9708081 | 0.98 | AGTR1 (0.51) | AGTR2AGTR1PPARGMEN1KMT2A | |
| SCHEMBL9708175 | 0.95 | AGTR1 (0.48) | AGTR2AGTR1PPARGMEN1KMT2A | |
| SCHEMBL9708525 | 0.92 | TPH2 (0.47) | AGTR2AGTR1PPARGMEN1KMT2A | |
| SCHEMBL9708426 | 0.90 | MEN1 (0.53) | AGTR2AGTR1MEN1KMT2A | |
| SCHEMBL9708766 | 0.90 | AGTR1 (0.55) | AGTR2AGTR1PPARG | |
| SCHEMBL9707282 | 0.90 | AGTR1 (0.55) | AGTR2AGTR1PPARG | |
| SCHEMBL9707286 | 0.89 | AGTR1 (0.50) | AGTR2AGTR1MEN1KMT2A | |
| SCHEMBL9707594 | 0.89 | AGTR1 (0.47) | AGTR2AGTR1PPARGMEN1KMT2A | |
| SCHEMBL9708313 | 0.89 | MEN1 (0.44) | AGTR2AGTR1PPARGMEN1KMT2A | |
| SCHEMBL9707393 | 0.88 | AGTR1 (0.54) | AGTR2AGTR1PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992007852-A1 | BIPHENYLALKYL XANTHINE COMPOUNDS FOR TREATMENT OF CARDIOVASCULAR DISORDERS | G.D. SEARLE & CO. (US) | 1992-05-14 | — | — | WO | disclosed |