Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR1 | P30556 | 6/20 | 0.47 |
| ▸ | AGTR2 | P50052 | 6/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | PKM | P14618 | 2/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | PPARG | P37231 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9708458 | 0.98 | KDM4E (0.46) | AGTR1AGTR2KDM4EALDH1A1PKM | |
| SCHEMBL9707568 | 0.95 | ALDH1A1 (0.48) | AGTR1AGTR2KDM4EALDH1A1PKM | |
| SCHEMBL9707286 | 0.93 | AGTR1 (0.50) | AGTR1AGTR2KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL9707846 | 0.92 | ALDH1A1 (0.49) | AGTR1AGTR2KDM4EALDH1A1PKM | |
| SCHEMBL9708270 | 0.92 | MEN1 (0.49) | AGTR1AGTR2KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL9708233 | 0.91 | TPH1 (0.49) | AGTR1AGTR2KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL9708426 | 0.91 | MEN1 (0.53) | AGTR1AGTR2MEN1KMT2A | |
| SCHEMBL9708208 | 0.89 | ALDH1A1 (0.49) | AGTR1AGTR2KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL9707992 | 0.89 | USP2 (0.51) | AGTR1AGTR2ALDH1A1MEN1KMT2A | |
| SCHEMBL9708417 | 0.89 | AGTR2 (0.53) | AGTR1AGTR2MEN1KMT2APPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992007852-A1 | BIPHENYLALKYL XANTHINE COMPOUNDS FOR TREATMENT OF CARDIOVASCULAR DISORDERS | G.D. SEARLE & CO. (US) | 1992-05-14 | — | — | WO | disclosed |