Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DCTPP1 | Q9H773 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | PPARG | P37231 | 3/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.37 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.37 |
| ▸ | USP1 | O94782 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 3/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9708605 | 0.91 | ADORA2B (0.42) | AGTR1AGTR2 | |
| SCHEMBL9707572 | 0.90 | AGTR1 (0.41) | DCTPP1KDM4EALDH1A1PKMPPARG | |
| SCHEMBL9707625 | 0.90 | KDM4E (0.41) | KDM4EMEN1KMT2APPARGAGTR1 | |
| SCHEMBL9708640 | 0.90 | USP1 (0.42) | DCTPP1KDM4EALDH1A1PKMMEN1 | |
| SCHEMBL9708298 | 0.89 | ADORA2B (0.40) | KDM4EMEN1KMT2AAGTR1AGTR2 | |
| SCHEMBL9708254 | 0.89 | AGTR1 (0.43) | PPARGAGTR1AGTR2 | |
| SCHEMBL9707673 | 0.88 | KDM4E (0.37) | DCTPP1KDM4EALDH1A1PKMMEN1 | |
| SCHEMBL9707747 | 0.88 | KDM4E (0.44) | DCTPP1KDM4EAGTR1AGTR2HPGD | |
| SCHEMBL9708271 | 0.88 | AGTR1 (0.42) | KMT2APPARGSMN1; SMN2AGTR1AGTR2 | |
| SCHEMBL9707446 | 0.87 | AGTR1 (0.47) | PPARGAGTR1AGTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992007852-A1 | BIPHENYLALKYL XANTHINE COMPOUNDS FOR TREATMENT OF CARDIOVASCULAR DISORDERS | G.D. SEARLE & CO. (US) | 1992-05-14 | — | — | WO | disclosed |