Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 1/20 | 0.39 |
| ▸ | CTSD | P07339 | 1/20 | 0.38 |
| ▸ | REN | P00797 | 2/20 | 0.37 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.36 |
| ▸ | BCHE | P06276 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
| ▸ | AKT1 | P31749 | 2/20 | 0.36 |
| ▸ | RORC | P51449 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.35 |
| ▸ | GLS | O94925 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7779326 | 0.80 | MEN1 (0.42) | FAAHCTSDRENMEN1KMT2A | |
| SCHEMBL7771883 | 0.72 | TSHR (0.51) | MEN1KMT2AMAPT | |
| SCHEMBL228875 | 0.65 | POLB (0.44) | FAAHHDAC8 | |
| SCHEMBL9604373 | 0.64 | NPY1R (0.42) | FAAHHDAC8HDAC6MAPT | |
| SCHEMBL9709176 | 0.63 | CNR2 (0.43) | EPHX2MEN1KMT2A | |
| SCHEMBL60235 | 0.61 | MEN1 (0.65) | EPHX2MEN1KMT2AHDAC8HDAC6 | |
| SCHEMBL699925 | 0.61 | MEN1 (0.71) | EPHX2MEN1KMT2AHDAC8HDAC6 | |
| SCHEMBL9516562 | 0.60 | POLB (0.37) | FAAHMEN1KMT2AMAPT | |
| SCHEMBL29248003 | 0.60 | MEN1 (0.59) | EPHX2MEN1KMT2AHDAC8HDAC6 | |
| SCHEMBL5087595 | 0.60 | KMT2A (0.59) | EPHX2BCHEACHEMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992020665-A1 | THIAZOLIDINE DERIVATIVES AND THEIR USE IN THERAPY | GLAXO GROUP LIMITED (GB) | 1992-11-26 | — | — | WO | claimed |