Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 2/20 | 0.62 |
| ▸ | MAOB | P27338 | 1/20 | 0.62 |
| ▸ | CDC25B | P30305 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 5/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | APAF1 | O14727 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | GALK1 | P51570 | 2/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.38 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.38 |
| ▸ | HK1 | P19367 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9709023 | 0.89 | MAOA (0.62) | MAOAMAOBCDC25BMEN1KMT2A | |
| SCHEMBL496444 | 0.88 | MAOA (0.48) | MAOAMAOBCDC25BCYP3A4CYP1A2 | |
| SCHEMBL1750489 | 0.83 | MEN1 (0.58) | MAOAMAOBCDC25BMEN1KMT2A | |
| SCHEMBL421291 | 0.77 | MAOA (1.00) | MAOAMAOBCDC25BMEN1KMT2A | |
| SCHEMBL29350676 | 0.77 | MAOA (1.00) | MAOAMAOBCDC25BMEN1KMT2A | |
| SCHEMBL6926901 | 0.75 | MAOA (0.95) | MAOAMAOBCDC25BMEN1KMT2A | |
| SCHEMBL3066734 | 0.75 | MAOA (0.87) | MAOAMAOBCDC25BMEN1KMT2A | |
| SCHEMBL19013209 | 0.71 | MAOA (0.87) | MAOAMAOBCDC25BMEN1KMT2A | |
| SCHEMBL1386281 | 0.70 | MEN1 (0.46) | MAOAMAOBCDC25BMEN1KMT2A | |
| SCHEMBL20618218 | 0.69 | MAOA (0.77) | MAOAMAOBCDC25BMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0471516-A1 | Tricyclic heterocyclic derivatives | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1992-02-19 | — | — | EP | disclosed |