Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.49 |
| ▸ | ACP1 | P24666 | 3/20 | 0.48 |
| ▸ | CD38 | P28907 | 2/20 | 0.48 |
| ▸ | ATM | Q13315 | 1/20 | 0.48 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.46 |
| ▸ | BDKRB1 | P46663 | 2/20 | 0.45 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9494718 | 0.88 | ACP1 (0.54) | KDM4EACP1CD38BDKRB1CYP2C19 | |
| SCHEMBL3058636 | 0.84 | CD38 (0.56) | ACP1CD38BDKRB1LTB4R2CYP2C19 | |
| SCHEMBL9709560 | 0.84 | CD38 (0.50) | KDM4EACP1CD38CYP2C19 | |
| Hydrochloric Acid SCHEMBL9494706 | 0.83 | CD38 (0.55) | ACP1CD38BDKRB1LTB4R2CYP2C19 | |
| SCHEMBL9709659 | 0.80 | LTB4R2 (0.47) | KDM4EATMLTB4R2 | |
| SCHEMBL9709750 | 0.79 | DHODH (0.59) | KDM4ELTB4R2 | |
| SCHEMBL3055538 | 0.79 | CD38 (0.50) | ACP1CD38LTB4R2CYP2C19 | |
| SCHEMBL1636608 | 0.77 | ATM (0.72) | KDM4EATMPLA2G2ACYP2C19 | |
| SCHEMBL9709741 | 0.76 | KDM4E (0.57) | KDM4EACP1LTB4R2 | |
| SCHEMBL9709700 | 0.75 | VCP (0.52) | CD38BDKRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992022533-A1 | 4-AMINOQUINOLINES AND PHARMACEUTICAL COMPOSITIONS THEREOF | THE UPJOHN COMPANY (US) | 1992-12-23 | — | — | WO | disclosed |