Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CD38 | P28907 | 3/20 | 0.50 |
| ▸ | ACP1 | P24666 | 4/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.45 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.45 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | GALR3 | O60755 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | NCF1 | P14598 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27791830 | 0.90 | CYP2C19 (0.47) | CD38ACP1CYP2C19OPRK1KDM4E | |
| SCHEMBL9494718 | 0.90 | ACP1 (0.54) | CD38ACP1CYP2C19AGTR1AGTR2 | |
| SCHEMBL9709861 | 0.87 | BDKRB1 (0.47) | CD38AGTR1AGTR2 | |
| SCHEMBL3058636 | 0.87 | CD38 (0.56) | CD38ACP1CYP2C19OPRK1HTT | |
| Hydrochloric Acid SCHEMBL9494706 | 0.86 | CD38 (0.55) | CD38ACP1CYP2C19OPRK1HTT | |
| SCHEMBL9709650 | 0.84 | KDM4E (0.49) | CD38ACP1CYP2C19KDM4E | |
| SCHEMBL27813010 | 0.82 | OPRK1 (0.46) | CD38CYP2C19OPRK1KDM4EHTT | |
| SCHEMBL3055538 | 0.81 | CD38 (0.50) | CD38ACP1CYP2C19OPRK1HTT | |
| SCHEMBL9709700 | 0.77 | VCP (0.52) | CD38AGTR1AGTR2MEN1KMT2A | |
| SCHEMBL9709749 | 0.75 | CD38 (0.64) | CD38 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992022533-A1 | 4-AMINOQUINOLINES AND PHARMACEUTICAL COMPOSITIONS THEREOF | THE UPJOHN COMPANY (US) | 1992-12-23 | — | — | WO | claimed |
| WO-1992022533-A1 | 4-AMINOQUINOLINES AND PHARMACEUTICAL COMPOSITIONS THEREOF | THE UPJOHN COMPANY (US) | 1992-12-23 | — | — | WO | disclosed |