Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.57 |
| ▸ | DHODH | Q02127 | 1/20 | 0.54 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.53 |
| ▸ | PPARG | P37231 | 2/20 | 0.52 |
| ▸ | AGTR1 | P30556 | 2/20 | 0.50 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.50 |
| ▸ | BRS3 | P32247 | 1/20 | 0.49 |
| ▸ | ACP1 | P24666 | 1/20 | 0.49 |
| ▸ | PLK1 | P53350 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9709750 | 0.95 | DHODH (0.59) | KDM4EDHODHLTB4R2PPARGAGTR1 | |
| SCHEMBL9709740 | 0.93 | LTB4R2 (0.51) | KDM4EDHODHLTB4R2PPARGAGTR1 | |
| SCHEMBL9709569 | 0.87 | PPARG (0.48) | KDM4ELTB4R2PPARGAGTR1AGTR2 | |
| SCHEMBL3058636 | 0.86 | CD38 (0.56) | LTB4R2ACP1 | |
| Hydrochloric Acid SCHEMBL9494706 | 0.85 | CD38 (0.55) | LTB4R2ACP1 | |
| SCHEMBL9709862 | 0.80 | BDKRB1 (0.46) | DHODHLTB4R2AGTR1AGTR2 | |
| SCHEMBL9709673 | 0.79 | PDE4A (0.47) | AGTR1AGTR2ACP1 | |
| SCHEMBL9183186 | 0.79 | KDM4E (0.57) | KDM4EDHODHPPARGAGTR1AGTR2 | |
| SCHEMBL7834869 | 0.79 | DHODH (0.59) | DHODHPPARGAGTR1AGTR2BRS3 | |
| SCHEMBL9709723 | 0.78 | AGTR1 (0.47) | PPARGAGTR1AGTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992022533-A1 | 4-AMINOQUINOLINES AND PHARMACEUTICAL COMPOSITIONS THEREOF | THE UPJOHN COMPANY (US) | 1992-12-23 | — | — | WO | claimed |