Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BDKRB1 | P46663 | 12/20 | 0.47 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.43 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.43 |
| ▸ | CD38 | P28907 | 3/20 | 0.41 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.39 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9709560 | 0.87 | CD38 (0.50) | AGTR1AGTR2CD38 | |
| SCHEMBL27791830 | 0.78 | CYP2C19 (0.47) | CD38 | |
| SCHEMBL9494718 | 0.77 | ACP1 (0.54) | BDKRB1AGTR1AGTR2CD38 | |
| SCHEMBL9709862 | 0.76 | BDKRB1 (0.46) | BDKRB1AGTR1AGTR2 | |
| SCHEMBL9709569 | 0.75 | PPARG (0.48) | BDKRB1AGTR1AGTR2ADRA1A | |
| SCHEMBL9377391 | 0.75 | MAPT (0.48) | BDKRB1 | |
| SCHEMBL3058636 | 0.74 | CD38 (0.56) | BDKRB1CD38 | |
| SCHEMBL9709799 | 0.74 | CD38 (0.47) | BDKRB1AGTR1AGTR2CD38 | |
| SCHEMBL9709866 | 0.73 | AGTR1 (0.47) | AGTR1AGTR2 | |
| Hydrochloric Acid SCHEMBL9494706 | 0.73 | CD38 (0.55) | BDKRB1CD38 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992022533-A1 | 4-AMINOQUINOLINES AND PHARMACEUTICAL COMPOSITIONS THEREOF | THE UPJOHN COMPANY (US) | 1992-12-23 | — | — | WO | disclosed |