Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BDKRB1 | P46663 | 7/20 | 0.46 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.44 |
| ▸ | AGTR1 | P30556 | 3/20 | 0.44 |
| ▸ | AGTR2 | P50052 | 3/20 | 0.44 |
| ▸ | DHODH | Q02127 | 1/20 | 0.43 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9709569 | 0.93 | PPARG (0.48) | BDKRB1LTB4R2AGTR1AGTR2 | |
| SCHEMBL9709740 | 0.87 | LTB4R2 (0.51) | LTB4R2AGTR1AGTR2DHODH | |
| SCHEMBL9709660 | 0.83 | AGTR1 (0.45) | LTB4R2AGTR1AGTR2 | |
| SCHEMBL9709868 | 0.82 | DHODH (0.46) | BDKRB1AGTR1AGTR2DHODH | |
| SCHEMBL9709741 | 0.80 | KDM4E (0.57) | LTB4R2AGTR1AGTR2DHODH | |
| SCHEMBL9709750 | 0.79 | DHODH (0.59) | LTB4R2AGTR1AGTR2DHODH | |
| SCHEMBL9709589 | 0.79 | AGTR1 (0.49) | AGTR1AGTR2 | |
| SCHEMBL9709723 | 0.77 | AGTR1 (0.47) | AGTR1AGTR2 | |
| SCHEMBL9709718 | 0.76 | AGTR1 (0.42) | AGTR1AGTR2 | |
| SCHEMBL9709861 | 0.76 | BDKRB1 (0.47) | BDKRB1AGTR1AGTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992022533-A1 | 4-AMINOQUINOLINES AND PHARMACEUTICAL COMPOSITIONS THEREOF | THE UPJOHN COMPANY (US) | 1992-12-23 | — | — | WO | claimed |
| WO-1992022533-A1 | 4-AMINOQUINOLINES AND PHARMACEUTICAL COMPOSITIONS THEREOF | THE UPJOHN COMPANY (US) | 1992-12-23 | — | — | WO | disclosed |