Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 5/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | AGTR1 | P30556 | 5/20 | 0.46 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.46 |
| ▸ | BDKRB1 | P46663 | 3/20 | 0.46 |
| ▸ | BRS3 | P32247 | 1/20 | 0.46 |
| ▸ | PLK1 | P53350 | 1/20 | 0.45 |
| ▸ | AGTR2 | P50052 | 3/20 | 0.45 |
| ▸ | ABCC3 | O15438 | 1/20 | 0.44 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.44 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.44 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | ACE | P12821 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9709862 | 0.93 | BDKRB1 (0.46) | AGTR1LTB4R2BDKRB1AGTR2 | |
| SCHEMBL9709741 | 0.87 | KDM4E (0.57) | PPARGKDM4EAGTR1LTB4R2BRS3 | |
| SCHEMBL9709868 | 0.85 | DHODH (0.46) | KDM4EAGTR1BDKRB1BRS3PLK1 | |
| SCHEMBL9709750 | 0.82 | DHODH (0.59) | PPARGKDM4EAGTR1LTB4R2BRS3 | |
| SCHEMBL9709740 | 0.80 | LTB4R2 (0.51) | PPARGKDM4EAGTR1LTB4R2AGTR2 | |
| SCHEMBL9709803 | 0.80 | AGTR1 (0.41) | AGTR1AGTR2PDE4APDE4DPDE3A | |
| SCHEMBL9709660 | 0.76 | AGTR1 (0.45) | AGTR1LTB4R2AGTR2ALDH1A1NPSR1 | |
| SCHEMBL9709861 | 0.75 | BDKRB1 (0.47) | AGTR1BDKRB1AGTR2ADRA1A | |
| SCHEMBL9709925 | 0.75 | PDE4A (0.42) | AGTR1AGTR2PDE4APDE4DPDE3A | |
| SCHEMBL9709947 | 0.74 | AGTR1 (0.40) | AGTR1BDKRB1AGTR2PDE4APDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992022533-A1 | 4-AMINOQUINOLINES AND PHARMACEUTICAL COMPOSITIONS THEREOF | THE UPJOHN COMPANY (US) | 1992-12-23 | — | — | WO | claimed |
| WO-1992022533-A1 | 4-AMINOQUINOLINES AND PHARMACEUTICAL COMPOSITIONS THEREOF | THE UPJOHN COMPANY (US) | 1992-12-23 | — | — | WO | disclosed |