Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 5/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | GLA | P06280 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.44 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | DRD2 | P14416 | 1/20 | 0.43 |
| ▸ | DRD4 | P21917 | 1/20 | 0.43 |
| ▸ | DRD3 | P35462 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9710290 | 0.83 | HPGD (0.55) | MAPTLMNAHPGDGAAHDAC1 | |
| SCHEMBL9710275 | 0.81 | LMNA (0.59) | MAPTLMNAHPGDGAAHDAC1 | |
| SCHEMBL9710291 | 0.81 | LMNA (0.43) | LMNAHPGDGAAHDAC1SMN1; SMN2 | |
| SCHEMBL10435997 | 0.78 | MAPT (0.56) | HTTMAPTLMNAHPGDGAA | |
| SCHEMBL9710122 | 0.74 | EPHX2 (0.62) | HTTMAPTHPGDGAASMN1; SMN2 | |
| SCHEMBL6848785 | 0.74 | HTT (0.83) | HTTMAPTHPGDGAAHDAC1 | |
| SCHEMBL9710046 | 0.72 | DDR1 (0.55) | HTTMAPTLMNAHPGDGAA | |
| SCHEMBL6848908 | 0.70 | SMN1; SMN2 (0.66) | MAPTLMNAHPGDSMN1; SMN2KMT2A | |
| SCHEMBL9710223 | 0.69 | ALDH1A1 (0.47) | MAPTLMNAHPGDGAANPC1 | |
| SCHEMBL11901119 | 0.69 | HPGD (0.84) | HTTMAPTLMNAHPGDGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992021668-A1 | BENZOTHIAZEPINONES AND THEIR USE AS ANTICONVULSANTS | THE BOOTS COMPANY PLC (GB) | 1992-12-10 | — | — | WO | disclosed |