Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | ERCC1 | P07992 | 1/20 | 0.40 |
| ▸ | ERCC4 | Q92889 | 1/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.40 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3459833 | 0.84 | GAA (0.55) | LMNAMEN1KMT2AGAAMAPK14 | |
| SCHEMBL9710275 | 0.84 | LMNA (0.59) | LMNAMEN1KMT2AGAAHDAC6 | |
| SCHEMBL9710290 | 0.84 | HPGD (0.55) | LMNAMEN1KMT2AGAAHDAC6 | |
| SCHEMBL9710201 | 0.81 | HTT (0.50) | LMNAMEN1KMT2AGAAHPGD | |
| SCHEMBL9710216 | 0.78 | HPGD (0.51) | LMNAGAAHPGDALDH1A1NPC1 | |
| SCHEMBL3460926 | 0.77 | LMNA (0.64) | LMNAROCK2RAB9ASMN1; SMN2 | |
| SCHEMBL9710223 | 0.75 | ALDH1A1 (0.47) | LMNAMEN1KMT2AGAAHPGD | |
| SCHEMBL9710046 | 0.75 | DDR1 (0.55) | LMNAMEN1KMT2AGAAHPGD | |
| SCHEMBL4518408 | 0.73 | MAPK14 (0.52) | LMNAMEN1KMT2AMAPK14ROCK2 | |
| SCHEMBL5644578 | 0.72 | GAA (0.52) | LMNAMEN1KMT2AGAAHDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992021668-A1 | BENZOTHIAZEPINONES AND THEIR USE AS ANTICONVULSANTS | THE BOOTS COMPANY PLC (GB) | 1992-12-10 | — | — | WO | disclosed |