Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 5/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.55 |
| ▸ | LMNA | P02545 | 4/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 3/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | CCR5 | P51681 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9710275 | 0.84 | LMNA (0.59) | HPGDALDH1A1LMNAMAPTKDM4E | |
| SCHEMBL9710291 | 0.84 | LMNA (0.43) | HPGDALDH1A1LMNAPOLBNPC1 | |
| SCHEMBL9710201 | 0.83 | HTT (0.50) | HPGDALDH1A1LMNAMAPTPOLB | |
| SCHEMBL8400125 | 0.76 | POLB (0.59) | HPGDALDH1A1POLBNPC1RAB9A | |
| SCHEMBL13947260 | 0.73 | POLB (0.57) | HPGDALDH1A1LMNAMAPTKDM4E | |
| SCHEMBL4521046 | 0.71 | ALDH1A1 (1.00) | HPGDALDH1A1LMNAMAPTKDM4E | |
| SCHEMBL24269642 | 0.70 | HPGD (0.58) | HPGDALDH1A1LMNAPOLBMEN1 | |
| SCHEMBL5648574 | 0.70 | LMNA (0.75) | HPGDALDH1A1LMNAMAPTKDM4E | |
| SCHEMBL9710046 | 0.69 | DDR1 (0.55) | HPGDALDH1A1LMNAMAPTNPC1 | |
| SCHEMBL9710223 | 0.69 | ALDH1A1 (0.47) | HPGDALDH1A1LMNAMAPTNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992021668-A1 | BENZOTHIAZEPINONES AND THEIR USE AS ANTICONVULSANTS | THE BOOTS COMPANY PLC (GB) | 1992-12-10 | — | — | WO | disclosed |