Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DDR1 | Q08345 | 5/20 | 0.55 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | TTR | P02766 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.42 |
| ▸ | ERCC1 | P07992 | 1/20 | 0.42 |
| ▸ | ERCC4 | Q92889 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | BCHE | P06276 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9710223 | 0.90 | ALDH1A1 (0.47) | DDR1HPGDALDH1A1TTRMAPT | |
| SCHEMBL3460904 | 0.77 | EPHX2 (0.57) | HPGDALDH1A1TTREPHX2ERCC1 | |
| SCHEMBL15686088 | 0.75 | HPGD (0.68) | DDR1HPGDALDH1A1TTRMAPT | |
| SCHEMBL5643080 | 0.75 | SMN1; SMN2 (0.57) | HPGDALDH1A1MAPTEPHX2MEN1 | |
| SCHEMBL9710291 | 0.75 | LMNA (0.43) | HPGDALDH1A1ERCC1ERCC4NPC1 | |
| SCHEMBL9710216 | 0.75 | HPGD (0.51) | HPGDALDH1A1TTRMAPTHTT | |
| SCHEMBL9710122 | 0.73 | EPHX2 (0.62) | HPGDALDH1A1MAPTHTTEPHX2 | |
| SCHEMBL9710201 | 0.72 | HTT (0.50) | HPGDALDH1A1MAPTHTTNPC1 | |
| SCHEMBL16528035 | 0.71 | DDR1 (1.00) | DDR1ALDH1A1 | |
| SCHEMBL2914008 | 0.70 | HPGD (0.65) | HPGDALDH1A1MAPTHTTNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992021668-A1 | BENZOTHIAZEPINONES AND THEIR USE AS ANTICONVULSANTS | THE BOOTS COMPANY PLC (GB) | 1992-12-10 | — | — | WO | disclosed |