Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 5/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.43 |
| ▸ | NAMPT | P43490 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | TTR | P02766 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2914008 | 0.81 | HPGD (0.65) | HPGDALDH1A1POLBHTTLMNA | |
| SCHEMBL9710291 | 0.78 | LMNA (0.43) | HPGDALDH1A1POLBLMNASMN1; SMN2 | |
| SCHEMBL9710223 | 0.75 | ALDH1A1 (0.47) | HPGDALDH1A1LMNAMAPTNPC1 | |
| SCHEMBL9710046 | 0.75 | DDR1 (0.55) | HPGDALDH1A1HTTLMNAMAPT | |
| SCHEMBL3459833 | 0.75 | GAA (0.55) | HPGDALDH1A1LMNAGAA | |
| SCHEMBL29114040 | 0.71 | HPGD (0.56) | HPGDALDH1A1POLBHTTLMNA | |
| SCHEMBL20804370 | 0.71 | HPGD (0.67) | HPGDALDH1A1POLBHTTLMNA | |
| SCHEMBL3460904 | 0.70 | EPHX2 (0.57) | HPGDALDH1A1POLBNPC1EPHX2 | |
| SCHEMBL1568699 | 0.70 | NAMPT (0.69) | HPGDHTTLMNANPC1NAMPT | |
| SCHEMBL31396790 | 0.70 | HPGD (0.59) | HPGDALDH1A1HTTLMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992021668-A1 | BENZOTHIAZEPINONES AND THEIR USE AS ANTICONVULSANTS | THE BOOTS COMPANY PLC (GB) | 1992-12-10 | — | — | WO | disclosed |