Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TUBB4A | P04350 | 5/20 | 0.40 |
| ▸ | TUBB | P07437 | 5/20 | 0.40 |
| ▸ | TUBA3C | P0DPH7 | 5/20 | 0.40 |
| ▸ | TUBA1B | P68363 | 5/20 | 0.40 |
| ▸ | TUBA4A | P68366 | 5/20 | 0.40 |
| ▸ | TUBB4B | P68371 | 5/20 | 0.40 |
| ▸ | TUBB3 | Q13509 | 5/20 | 0.40 |
| ▸ | TUBB2A | Q13885 | 5/20 | 0.40 |
| ▸ | TUBB8 | Q3ZCM7 | 5/20 | 0.40 |
| ▸ | TUBA3E | Q6PEY2 | 5/20 | 0.40 |
| ▸ | TUBA1A | Q71U36 | 5/20 | 0.40 |
| ▸ | TUBA1C | Q9BQE3 | 5/20 | 0.40 |
| ▸ | TUBB6 | Q9BUF5 | 5/20 | 0.40 |
| ▸ | TUBB2B | Q9BVA1 | 5/20 | 0.40 |
| ▸ | TUBB1 | Q9H4B7 | 5/20 | 0.40 |
| ▸ | EGFR | P00533 | 1/20 | 0.40 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.39 |
| ▸ | HTR1A | P08908 | 1/20 | 0.39 |
| ▸ | PGR | P06401 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9381708 | 0.85 | NFE2L2 (0.38) | NFE2L2PGRLMNASMN1; SMN2ADORA2A | |
| SCHEMBL8502930 | 0.84 | HTR1A (0.42) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL2388924 | 0.83 | PGR (0.41) | HTR1APGRLMNAKMT2A | |
| SCHEMBL5599422 | 0.83 | PTGS2 (0.43) | NFE2L2LMNASMN1; SMN2ADORA2AADORA1 | |
| SCHEMBL31265222 | 0.83 | PTGS2 (0.43) | NFE2L2LMNASMN1; SMN2ADORA2AADORA1 | |
| SCHEMBL27535808 | 0.80 | DRD2 (0.42) | NFE2L2 | |
| SCHEMBL7221831 | 0.78 | DRD2 (0.44) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL8004806 | 0.77 | CA12 (0.39) | NFE2L2PGR | |
| SCHEMBL9710746 | 0.77 | CA12 (0.41) | LMNASMN1; SMN2KMT2A | |
| SCHEMBL29414143 | 0.76 | CA1 (0.50) | NFE2L2LMNASMN1; SMN2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992020642-A1 | BIS MONO-AND BICYCLIC ARYL AND HETEROARYL COMPOUNDS WHICH INHIBIT EGF AND/OR PDGF RECEPTOR TYROSINE KINASE | RHONE-POULENC RORER INTERNATIONAL (HOLDINGS) INC. (US) | 1992-11-26 | — | — | WO | disclosed |