Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.34 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.34 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.33 |
| ▸ | HPD | P32754 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | SRD5A1 | P18405 | 2/20 | 0.32 |
| ▸ | AR | P10275 | 1/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.32 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | CCR2 | P41597 | 2/20 | 0.31 |
| ▸ | CCR1 | P32246 | 1/20 | 0.31 |
| ▸ | CCR5 | P51681 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9710947 | 0.84 | KDM4E (0.36) | LMNAPDE4BPDE4DALDH1A1KDM4E | |
| SCHEMBL9711130 | 0.83 | — | — | |
| SCHEMBL9710925 | 0.81 | PPOX (0.43) | LMNAALDH1A1MAPTMAPK1HSD17B10 | |
| SCHEMBL9710816 | 0.79 | CCR2 (0.34) | PDE4BPDE4DCCR2CCR1CCR5 | |
| SCHEMBL9710650 | 0.78 | CCR2 (0.35) | PDE4BPDE4DCCR2CCR1CCR5 | |
| SCHEMBL9711057 | 0.72 | AOC3 (0.34) | PDE4BPDE4DS1PR4S1PR1S1PR5 | |
| SCHEMBL9710638 | 0.71 | KDM4E (0.40) | ALDH1A1KDM4EHPGD | |
| SCHEMBL10911510 | 0.71 | ALDH1A1 (0.51) | LMNAPDE4BPDE4DALDH1A1KDM4E | |
| SCHEMBL31442447 | 0.71 | ALDH1A1 (0.51) | LMNAPDE4BPDE4DALDH1A1KDM4E | |
| SCHEMBL9710867 | 0.71 | MAPK8 (0.44) | LMNAPDE4BPDE4DALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992021662-A1 | POSSIBLY CONDENSED PHENYLIMIDAZOLONES AND PYRIMIDINONES AS HERBICIDES; INTERMEDIATES | DOWELANCO (US) | 1992-12-10 | — | — | WO | disclosed |