Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK8 | P45983 | 1/20 | 0.44 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.44 |
| ▸ | CNR1 | P21554 | 2/20 | 0.43 |
| ▸ | AR | P10275 | 3/20 | 0.40 |
| ▸ | PDE4A | P27815 | 2/20 | 0.40 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.40 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.40 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.40 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | PPARG | P37231 | 1/20 | 0.39 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.39 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9710842 | 0.80 | RGS4 (0.50) | MAPK8MAPK9CNR1ARPDE4A | |
| SCHEMBL9711057 | 0.75 | AOC3 (0.34) | PDE4BPDE4D | |
| SCHEMBL9711065 | 0.72 | KDM4E (0.36) | KDM4EKMT2ALMNAMEN1 | |
| SCHEMBL9710883 | 0.71 | LMNA (0.35) | ARPDE4BPDE4DALDH1A1KDM4E | |
| SCHEMBL9710947 | 0.68 | KDM4E (0.36) | CNR1PDE4BPDE4DALDH1A1KDM4E | |
| SCHEMBL31743576 | 0.66 | CCR2 (0.54) | MAPK8MAPK9ALDH1A1KDM4ENPSR1 | |
| SCHEMBL9710816 | 0.66 | CCR2 (0.34) | PDE4BPDE4DCCR2 | |
| SCHEMBL9710650 | 0.65 | CCR2 (0.35) | PDE4BPDE4DKMT2ACCR2 | |
| SCHEMBL5526856 | 0.65 | PDE9A (0.52) | MAPK8MAPK9CNR1ALDH1A1KDM4E | |
| SCHEMBL31442447 | 0.63 | ALDH1A1 (0.51) | PDE4BPDE4DALDH1A1KDM4EKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992021662-A1 | POSSIBLY CONDENSED PHENYLIMIDAZOLONES AND PYRIMIDINONES AS HERBICIDES; INTERMEDIATES | DOWELANCO (US) | 1992-12-10 | — | — | WO | disclosed |
| US-5153316-A | Post and preemergence herbicides | DOWELANCO | 1992-10-06 | — | — | US | disclosed |