SCHEMBL9710947

SCHEMBL9710947

N#Cc1c2n(c(=O)n1-c1ccc(Cl)cc1F)CCCC2

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 2/20 0.36
USP2 O75604 1/20 0.36
KMT2A Q03164 2/20 0.36
HPGD P15428 2/20 0.36
MEN1 O00255 1/20 0.36
RECQL P46063 1/20 0.36
LMNA P02545 1/20 0.36
NPC1 O15118 1/20 0.36
PDE4B Q07343 1/20 0.34
PDE4D Q08499 1/20 0.34
ALDH1A1 P00352 3/20 0.34
F10 P00742 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.32
PPARG P37231 1/20 0.32
RORC P51449 1/20 0.32
TP53 P04637 1/20 0.32
THRB P10828 1/20 0.32
CNR1 P21554 1/20 0.32
CHEK1 O14757 1/20 0.32
AVPR2 P30518 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9710638 0.88 KDM4E (0.40) KDM4EUSP2KMT2AHPGDMEN1
SCHEMBL9710883 0.84 LMNA (0.35) KDM4EHPGDLMNANPC1PDE4B
SCHEMBL9710708 0.82 PPARG (0.33) ALDH1A1SMN1; SMN2PPARGRORC
SCHEMBL9710794 0.82 RORC (0.35) RECQLALDH1A1SMN1; SMN2PPARGRORC
SCHEMBL9710597 0.80 KDM4E (0.42) KDM4EUSP2KMT2AHPGDMEN1
SCHEMBL9710798 0.79 PPOX (0.44) KDM4ELMNAALDH1A1SMN1; SMN2PPARG
SCHEMBL9710749 0.79 RORC (0.39) KMT2AHPGDMEN1LMNAALDH1A1
SCHEMBL9710926 0.79 HPGD (0.43) KDM4EUSP2KMT2AHPGDMEN1
SCHEMBL9710816 0.79 CCR2 (0.34) PDE4BPDE4DF10
SCHEMBL9710809 0.78 PPOX (0.44) KDM4ELMNAALDH1A1SMN1; SMN2PPARG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-1992021662-A1 POSSIBLY CONDENSED PHENYLIMIDAZOLONES AND PYRIMIDINONES AS HERBICIDES; INTERMEDIATES DOWELANCO (US) 1992-12-10 WO disclosed
US-5153316-A Post and preemergence herbicides DOWELANCO 1992-10-06 US disclosed