Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMO | O15229 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | PYGL | P06737 | 2/20 | 0.39 |
| ▸ | PYGM | P11217 | 2/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.39 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.38 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.37 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.36 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9711757 | 0.83 | RAB9A (0.44) | TSHRMAP2K1HTTNPC1MAPT | |
| SCHEMBL9711809 | 0.81 | PARP1 (0.42) | OPRM1OPRK1LMNAOPRD1KDM2B | |
| SCHEMBL9711637 | 0.79 | LMNA (0.32) | LMNAMAP2K1MEN1RAB9AKMT2A | |
| SCHEMBL9711460 | 0.78 | ALDH1A1 (0.44) | TSHRLMNAPOLBSLC6A2SLC6A4 | |
| SCHEMBL9711493 | 0.77 | CYP1A2 (0.49) | TSHRLMNAHTTCYP2D6MEN1 | |
| SCHEMBL9711502 | 0.77 | TPMT (0.37) | HTTNPC1MAPTRAB9AMAPK1 | |
| SCHEMBL9711452 | 0.77 | NPC1 (0.44) | TSHRHPGDLMNAPOLBKDM4E | |
| SCHEMBL8466743 | 0.76 | MAPT (0.49) | LMNAPOLBHTTKDM4ENPC1 | |
| SCHEMBL9711773 | 0.76 | HPGD (0.43) | TSHRHPGDLMNAMEN1NPC1 | |
| SCHEMBL9711735 | 0.75 | NPC1 (0.49) | HPGDPOLBMEN1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5114461-A | Herbicides | MAY & BAKER LIMITED (GB) | 1992-05-19 | — | — | US | disclosed |
| EP-0278742-A2 | Cyclic diones | MAY & BAKER LIMITED (GB) | 1988-08-17 | — | — | EP | disclosed |