Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | PARP1 | P09874 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | F2RL1 | P55085 | 3/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | MBTD1 | Q05BQ5 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | HRH1 | P35367 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | L3MBTL3 | Q96JM7 | 2/20 | 0.36 |
| ▸ | L3MBTL4 | Q8NA19 | 1/20 | 0.36 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9711809 | 0.83 | PARP1 (0.42) | NPC1RAB9APARP1MEN1KMT2A | |
| SCHEMBL9711621 | 0.83 | PARP1 (0.42) | NPC1RAB9APARP1ALDH1A1HPGD | |
| SCHEMBL9711452 | 0.82 | NPC1 (0.44) | NPC1RAB9APARP1HPGDPOLB | |
| SCHEMBL9711491 | 0.80 | CES2 (0.49) | ALDH1A1HPGDMEN1KMT2APOLB | |
| SCHEMBL9711489 | 0.79 | CES2 (0.50) | ALDH1A1TP53MEN1KMT2AL3MBTL1 | |
| SCHEMBL9711773 | 0.78 | HPGD (0.43) | NPC1RAB9AALDH1A1HPGDMEN1 | |
| SCHEMBL9711601 | 0.77 | HSD11B1 (0.44) | — | |
| SCHEMBL9711527 | 0.75 | KMO (0.47) | NPC1RAB9AALDH1A1TP53HPGD | |
| SCHEMBL9711541 | 0.75 | PARP10 (0.36) | NPC1RAB9APARP1ALDH1A1MEN1 | |
| SCHEMBL9711528 | 0.74 | F2RL1 (0.42) | NPC1RAB9APARP1ALDH1A1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5114461-A | Herbicides | MAY & BAKER LIMITED (GB) | 1992-05-19 | — | — | US | disclosed |
| EP-0278742-A2 | Cyclic diones | MAY & BAKER LIMITED (GB) | 1988-08-17 | — | — | EP | disclosed |