Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP10 | Q53GL7 | 2/20 | 0.36 |
| ▸ | PARP11 | Q9NR21 | 1/20 | 0.36 |
| ▸ | PARP1 | P09874 | 1/20 | 0.36 |
| ▸ | FLT1 | P17948 | 1/20 | 0.34 |
| ▸ | FLT4 | P35916 | 1/20 | 0.34 |
| ▸ | KDR | P35968 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 3/20 | 0.33 |
| ▸ | RAB9A | P51151 | 3/20 | 0.33 |
| ▸ | TDP2 | O95551 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 3/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.32 |
| ▸ | HBB | P68871 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9711534 | 0.80 | ITGB1 (0.38) | PARP10PARP11PARP1ALDH1A1NPC1 | |
| SCHEMBL9711452 | 0.80 | NPC1 (0.44) | PARP10PARP11PARP1NPC1RAB9A | |
| SCHEMBL9711711 | 0.80 | HPD (0.48) | PARP10PARP11PARP1ALDH1A1RAB9A | |
| SCHEMBL9711773 | 0.78 | HPGD (0.43) | ALDH1A1NPC1RAB9ALMNATSHR | |
| SCHEMBL9711735 | 0.75 | NPC1 (0.49) | PARP1ALDH1A1GAANPC1RAB9A | |
| SCHEMBL9711719 | 0.74 | PARP10 (0.36) | PARP10PARP11ALDH1A1GAAMEN1 | |
| SCHEMBL9711493 | 0.74 | CYP1A2 (0.49) | ALDH1A1GAANPC1RAB9AMAPT | |
| SCHEMBL9711583 | 0.72 | SMN1; SMN2 (0.44) | PARP10PARP1ALDH1A1NPC1RAB9A | |
| SCHEMBL9711707 | 0.72 | HPD (0.48) | ALDH1A1GAANPC1MAPTLMNA | |
| SCHEMBL9711472 | 0.70 | NOTUM (0.36) | LMNACRBN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5114461-A | Herbicides | MAY & BAKER LIMITED (GB) | 1992-05-19 | — | — | US | disclosed |
| EP-0278742-A2 | Cyclic diones | MAY & BAKER LIMITED (GB) | 1988-08-17 | — | — | EP | disclosed |