SCHEMBL9711719

SCHEMBL9711719

O=C1CCNC(=O)C1C(=O)c1ccccc1Br

nearest known ligand 0.65

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
PARP10 Q53GL7 1/20 0.36
PARP11 Q9NR21 1/20 0.36
F2RL1 P55085 1/20 0.36
GAA P10253 2/20 0.35
ALDH1A1 P00352 2/20 0.35
L3MBTL1 Q9Y468 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
ELANE P08246 1/20 0.35
MEN1 O00255 1/20 0.35
POLB P06746 1/20 0.35
KMT2A Q03164 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9711455 0.82 CES2 (0.42) ALDH1A1POLBKMT2A
SCHEMBL9711534 0.82 ITGB1 (0.38) PARP10PARP11ALDH1A1MEN1KMT2A
SCHEMBL9711769 0.78 MEN1 (0.43) GAAMEN1KMT2A
SCHEMBL9711619 0.78 PIN1 (0.48) ALDH1A1POLB
SCHEMBL8466743 0.78 MAPT (0.49) GAAALDH1A1L3MBTL1SMN1; SMN2POLB
SCHEMBL9711486 0.77 ALDH1A1 (0.44) GAAALDH1A1L3MBTL1SMN1; SMN2MEN1
SCHEMBL9711668 0.75 KDM4E (0.47) GAAALDH1A1L3MBTL1MEN1POLB
SCHEMBL9711452 0.75 NPC1 (0.44) PARP10PARP11POLB
SCHEMBL9711541 0.74 PARP10 (0.36) PARP10PARP11GAAALDH1A1MEN1
SCHEMBL9711735 0.74 NPC1 (0.49) F2RL1GAAALDH1A1L3MBTL1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5114461-A Herbicides MAY & BAKER LIMITED (GB) 1992-05-19 US disclosed
EP-0278742-A2 Cyclic diones MAY & BAKER LIMITED (GB) 1988-08-17 EP disclosed