Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 1/20 | 0.49 |
| ▸ | CES2 | O00748 | 1/20 | 0.43 |
| ▸ | CES1 | P23141 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.39 |
| ▸ | PARP1 | P09874 | 1/20 | 0.39 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.39 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.39 |
| ▸ | MGLL | Q99685 | 1/20 | 0.39 |
| ▸ | GSK3B | P49841 | 2/20 | 0.38 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | HPD | P32754 | 1/20 | 0.38 |
| ▸ | GPR6 | P46095 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9711814 | 0.85 | HPGD (0.41) | BACE1POLBMAPTSRD5A2ALDH1A1 | |
| SCHEMBL9711471 | 0.85 | CES2 (0.43) | BACE1CES2PARP1PARP10MEN1 | |
| SCHEMBL9711491 | 0.83 | CES2 (0.49) | CES2POLBPARP10SRD5A2ALDH1A1 | |
| SCHEMBL9711452 | 0.80 | NPC1 (0.44) | CES2CES1POLBHSD11B1PARP1 | |
| SCHEMBL9711493 | 0.80 | CYP1A2 (0.49) | CES2CES1MAPTALDH1A1MEN1 | |
| SCHEMBL9711502 | 0.80 | TPMT (0.37) | MAPTMGLLGSK3BPTPN1 | |
| SCHEMBL9711573 | 0.80 | CES2 (0.50) | CES2PARP1PARP10ALDH1A1MEN1 | |
| SCHEMBL8466743 | 0.80 | MAPT (0.49) | POLBMAPTALDH1A1 | |
| SCHEMBL9711517 | 0.79 | HPD (0.46) | CES2PARP1PARP10ALDH1A1MEN1 | |
| SCHEMBL9711457 | 0.78 | CA1 (0.42) | MAPTPARP10GSK3BALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5114461-A | Herbicides | MAY & BAKER LIMITED (GB) | 1992-05-19 | — | — | US | disclosed |
| EP-0278742-A2 | Cyclic diones | MAY & BAKER LIMITED (GB) | 1988-08-17 | — | — | EP | disclosed |