Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.41 |
| ▸ | PARP11 | Q9NR21 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9711471 | 0.86 | CES2 (0.43) | CES2SMN1; SMN2MEN1KMT2APARP10 | |
| SCHEMBL9711702 | 0.83 | BACE1 (0.49) | CES2POLBHPGDSRD5A2MEN1 | |
| SCHEMBL9711601 | 0.81 | HSD11B1 (0.44) | — | |
| SCHEMBL9711809 | 0.80 | PARP1 (0.42) | LMNAMEN1KMT2ANPSR1 | |
| SCHEMBL9711621 | 0.80 | PARP1 (0.42) | SMN1; SMN2HPGDMEN1KMT2AALDH1A1 | |
| SCHEMBL9711735 | 0.80 | NPC1 (0.49) | SMN1; SMN2POLBHPGDMEN1KMT2A | |
| SCHEMBL9711573 | 0.78 | CES2 (0.50) | CES2SMN1; SMN2HPGDMEN1KMT2A | |
| SCHEMBL9711517 | 0.77 | HPD (0.46) | CES2SMN1; SMN2HPGDMEN1KMT2A | |
| SCHEMBL9711648 | 0.76 | CES2 (0.43) | CES2SMN1; SMN2LMNAPOLBHPGD | |
| SCHEMBL9711489 | 0.75 | CES2 (0.50) | CES2LMNAPOLBMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5114461-A | Herbicides | MAY & BAKER LIMITED (GB) | 1992-05-19 | — | — | US | disclosed |
| EP-0278742-A2 | Cyclic diones | MAY & BAKER LIMITED (GB) | 1988-08-17 | — | — | EP | disclosed |