SCHEMBL9712243

SCHEMBL9712243

Cc1ccccc1-c1cc[c]c(C(C)C)c1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MCL1 Q07820 1/20 0.41
HTR7 P34969 3/20 0.38
TRPA1 O75762 1/20 0.36
CTSD P07339 1/20 0.36
BACE1 P56817 1/20 0.36
GRIA1 P42261 1/20 0.35
CACNG8 Q8WXS5 1/20 0.35
HTR1A P08908 1/20 0.35
LCK P06239 1/20 0.35
KDR P35968 1/20 0.35
JAK3 P52333 1/20 0.35
MAPK14 Q16539 1/20 0.35
AR P10275 1/20 0.35
PDK2 Q15119 1/20 0.35
ALOX5AP P20292 1/20 0.35
FEN1 P39748 1/20 0.35
CA12 O43570 2/20 0.34
CA9 Q16790 2/20 0.34
CA1 P00915 1/20 0.34
CA2 P00918 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28926416 0.80 HTR7 (0.38) MCL1HTR7TRPA1CTSDBACE1
SCHEMBL28684935 0.79 TRPA1 (0.40) TRPA1ALOX5APFEN1CYP2D6
SCHEMBL374592 0.78 MCL1 (0.45) MCL1HTR7TRPA1CTSDBACE1
SCHEMBL1370233 0.78 ALDH1A1 (0.36) MCL1
SCHEMBL28712375 0.76 LMNA (0.32) GRIA1CACNG8CA1CA2CYP1A2
SCHEMBL8125021 0.75 MCL1 (0.42) MCL1HTR7TRPA1CTSDBACE1
SCHEMBL10595614 0.75 MCL1 (0.42) MCL1HTR7TRPA1CTSDBACE1
SCHEMBL15638352 0.75 MCL1 (0.42) MCL1HTR7TRPA1CTSDBACE1
SCHEMBL28111316 0.74
SCHEMBL28167359 0.73 MCL1 (0.40) MCL1CA12CA9NR1H4EDNRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115991725-A Green phosphorescence bivalent platinum complex, preparation method and application thereof, and organic photoelectric device 中国石油化工股份有限公司 2023-04-21 CN claimed
WO-1992018092-A2 1-ARYLHETEROARYLALKYL SUBSTITUTED-1H-1,2,4-TRIAZOLE COMPOUNDS FOR TREATMENT OF CIRCULATORY DISORDERS G.D. SEARLE & CO. (US) 1992-10-29 WO claimed
WO-1992018092-A2 1-ARYLHETEROARYLALKYL SUBSTITUTED-1H-1,2,4-TRIAZOLE COMPOUNDS FOR TREATMENT OF CIRCULATORY DISORDERS G.D. SEARLE & CO. (US) 1992-10-29 WO disclosed