Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 3/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | GALR3 | O60755 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 3/20 | 0.32 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.31 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | ELANE | P08246 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6212223 | 0.81 | ALDH1A1 (0.47) | TSHRALDH1A1TDP1SMN1; SMN2HTT | |
| SCHEMBL9712499 | 0.80 | MAPT (0.46) | TSHRALDH1A1TDP1MEN1KMT2A | |
| SCHEMBL2355479 | 0.80 | LMNA (0.47) | ALDH1A1MEN1KMT2ASMN1; SMN2POLB | |
| SCHEMBL9712750 | 0.78 | CA2 (0.34) | NPSR1TSHRALDH1A1TDP1SMN1; SMN2 | |
| SCHEMBL9712433 | 0.78 | PDK1 (0.34) | NPSR1TSHRALDH1A1TDP1SMN1; SMN2 | |
| SCHEMBL1148444 | 0.74 | ALDH1A1 (0.50) | NPSR1TSHRALDH1A1TDP1SMN1; SMN2 | |
| SCHEMBL5082416 | 0.73 | TTR (0.41) | NPSR1TSHRALDH1A1TDP1MEN1 | |
| SCHEMBL9712448 | 0.73 | MAPT (0.40) | NPSR1ALDH1A1TDP1MEN1KMT2A | |
| SCHEMBL30663932 | 0.73 | ALDH1A1 (0.48) | TSHRALDH1A1TDP1KMT2ASMN1; SMN2 | |
| SCHEMBL9079084 | 0.71 | ALDH1A1 (0.46) | ALDH1A1TDP1SMN1; SMN2HTTMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5117057-A | Insecticidal N' substituted-N-N'-disubstituted-hydrazines | ROHM AND HAAS COMPANY (US) | 1992-05-26 | — | — | US | disclosed |