SCHEMBL9712480

SCHEMBL9712480

Cc1ccc(C(=O)c2ccccc2-c2ccccc2-c2ccccc2)c(C(=O)Cl)c1

nearest known ligand 0.50

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
HDAC7 Q8WUI4 1/20 0.50
L3MBTL1 Q9Y468 1/20 0.43
POLB P06746 2/20 0.39
PTGDR2 Q9Y5Y4 1/20 0.39
AKR1C3 P42330 1/20 0.39
MEN1 O00255 1/20 0.39
KMT2A Q03164 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.39
GAA P10253 1/20 0.39
BCAT2 O15382 1/20 0.38
NFE2L2 Q16236 1/20 0.37
NPSR1 Q6W5P4 1/20 0.36
UHRF1 Q96T88 1/20 0.36
FABP3 P05413 1/20 0.36
FABP4 P15090 1/20 0.36
HNF4A P41235 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL8172318 0.89 HDAC7 (0.44) HDAC7L3MBTL1POLBPTGDR2GAA
SCHEMBL7079259 0.79 HDAC7 (0.57) HDAC7L3MBTL1PTGDR2MEN1KMT2A
SCHEMBL3297211 0.78 BCAT2 (0.53) MEN1KMT2ASMN1; SMN2GAABCAT2
SCHEMBL10029709 0.78 BCAT2 (0.57) L3MBTL1MEN1KMT2ASMN1; SMN2GAA
SCHEMBL5484397 0.77 AKR1C3 (0.54) POLBAKR1C3MEN1KMT2ASMN1; SMN2
SCHEMBL8067577 0.73 BCAT2 (0.47) AKR1C3MEN1KMT2ASMN1; SMN2GAA
SCHEMBL30448294 0.73 AKR1C3 (0.67) L3MBTL1AKR1C3MEN1KMT2ASMN1; SMN2
SCHEMBL302204 0.73 CSNK2A1 (0.48) HDAC7POLBMEN1KMT2ASMN1; SMN2
SCHEMBL1580001 0.72 SLC6A3 (0.49) HDAC7L3MBTL1POLBAKR1C3MEN1
SCHEMBL30436191 0.72 SLC6A3 (0.49) HDAC7L3MBTL1POLBAKR1C3MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5117057-A Insecticidal N' substituted-N-N'-disubstituted-hydrazines ROHM AND HAAS COMPANY (US) 1992-05-26 US disclosed