SCHEMBL971255

SCHEMBL971255

Cn1cc(C(=O)Nc2ccc(F)cc2Br)c(C(F)F)n1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ATM Q13315 1/20 0.50
NPC1 O15118 4/20 0.47
RAB9A P51151 4/20 0.47
GAA P10253 1/20 0.45
NFKB1 P19838 2/20 0.44
NFKB2 Q00653 2/20 0.44
RELA Q04206 2/20 0.44
SMN1; SMN2 Q16637 2/20 0.44
HPGD P15428 1/20 0.44
RXFP1 Q9HBX9 3/20 0.44
MEN1 O00255 2/20 0.44
KMT2A Q03164 2/20 0.44
POLB P06746 1/20 0.44
LMNA P02545 2/20 0.44
L3MBTL1 Q9Y468 1/20 0.44
TSHR P16473 1/20 0.42
HSD17B10 Q99714 2/20 0.40
KDM4E B2RXH2 2/20 0.40
ALDH1A1 P00352 1/20 0.40
NPSR1 Q6W5P4 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1145131 0.87 HSD17B10 (0.41) ATMNPC1RAB9AGAASMN1; SMN2
SCHEMBL31375266 0.87 HSD17B10 (0.41) ATMNPC1RAB9AGAASMN1; SMN2
SCHEMBL972387 0.86 ALOX15 (0.53) POLBLMNA
SCHEMBL31475430 0.85 ATM (0.69) ATMHPGDRXFP1MEN1KMT2A
SCHEMBL973185 0.85 ATM (0.69) ATMHPGDRXFP1MEN1KMT2A
SCHEMBL12921935 0.85 ATM (0.69) ATMNPC1RAB9AGAANFKB1
SCHEMBL973582 0.82 LMNA (0.56) ATMNPC1RAB9AGAANFKB1
SCHEMBL13491718 0.82 CHRM3 (0.50) ATMRXFP1LMNAKDM4EALDH1A1
SCHEMBL4107508 0.81 ALDH1A1 (0.38) ATMNPC1RAB9ALMNAHSD17B10
SCHEMBL21069195 0.81 IRAK4 (0.40) LMNAIRAK4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 63 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025074340-A1 A PROCESS FOR PREPARATION OF AMINOBIPHENYL COMPOUNDS AND INTERMEDIATES THEREOF UPL LIMITED (IN) 2025-04-10 WO claimed
CN-119431246-A Bispyrimidine marked with dichloro benzene ring carbon-14 and preparation method thereof 浙江爱索拓科技有限公司 2025-02-14 CN claimed
EP-2285779-B1 Method for manufacturing aryl carboxamides BASF SE (DE) 2013-03-27 EP claimed
US-8350046-B2 Method for manufacturing aryl carboxamides BASF SE (DE) 2013-01-08 US claimed
EP-2257530-B1 PROCESS FOR PREPARING SUBSTITUTED BIPHENYLANILIDES BAYER CROPSCIENCE AG (DE) 2011-10-12 EP claimed
CN-102015649-A Method for producing aryl carboxamides BASF SE 2011-04-13 CN claimed
US-20110054183-A1 Method For Manufacturing Aryl Carboxamides BASF SE 2011-03-03 US claimed
EP-2285779-A1 METHOD FOR MANUFACTURING ARYL CARBOXAMIDES BASF SE (DE) 2011-02-23 EP claimed
US-20110003999-A1 Process for Preparing Substituted Biphenylanilides BAYER CROPSCIENCE AG (DE) 2011-01-06 US claimed
WO-2009135860-A1 METHOD FOR MANUFACTURING ARYL CARBOXAMIDES BASF SE (DE) 2009-11-12 WO claimed
EP-2093216-A1 Process for preparing substituted biphenylanilides Bayer CropScience AG (DE) 2009-08-26 EP claimed
WO-2025074340-A1 A PROCESS FOR PREPARATION OF AMINOBIPHENYL COMPOUNDS AND INTERMEDIATES THEREOF UPL LIMITED (IN) 2025-04-10 WO disclosed
CN-119431246-A Bispyrimidine marked with dichloro benzene ring carbon-14 and preparation method thereof 浙江爱索拓科技有限公司 2025-02-14 CN disclosed
EP-2300417-B1 PROCESS FOR PREPARING 2-(AMINOMETHYLIDENE)-4,4-DIFLUORO-3-OXOBUTYRIC ESTERS BASF SE (DE) 2015-07-22 EP disclosed
EP-2496560-B1 PROCESS FOR PREPARING 1,3-DISUBSTITUTED PYRAZOLE COMPOUNDS BASF SE (DE) 2015-04-22 EP disclosed
EP-2093216-A1 Process for preparing substituted biphenylanilides Bayer CropScience AG (DE) 2009-08-26 EP disclosed
EP-2049496-A2 3-DIFLUOROMETHYLPYRAZOLYLCARBOXANILIDES Bayer CropScience AG (DE) 2009-04-22 EP disclosed
WO-2008152138-A2 METHOD FOR PRODUCING DIFLUOROMETHYL-SUBSTITUTED PYRAZOLE COMPOUNDS BASF SE (DE) 2008-12-18 WO disclosed
WO-2008014905-A2 3-DIFLUOROMETHYLPYRAZOLYLCARBOXANILIDES BAYER CROPSCIENCE AG (DE) 2008-02-07 WO disclosed
WO-2008014905-A2 3-DIFLUOROMETHYLPYRAZOLYLCARBOXANILIDES BAYER CROPSCIENCE AG (DE) 2008-02-07 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110054183-A1 Method For Manufacturing Aryl Carboxamides H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16, CBR3, CBR1 ATM 3784/4885NPC1 3316/4885RAB9A 3848/4885
US-20110003999-A1 Process for Preparing Substituted Biphenylanilides DDT, PAH, THOP1 ATM 3682/4885NPC1 4610/4885RAB9A 1820/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.