Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP2K7 | O14733 | 1/20 | 0.44 |
| ▸ | ELANE | P08246 | 1/20 | 0.44 |
| ▸ | CDC25A | P30304 | 1/20 | 0.44 |
| ▸ | CDC25B | P30305 | 1/20 | 0.44 |
| ▸ | S100A4 | P26447 | 5/20 | 0.44 |
| ▸ | SOAT1 | P35610 | 8/20 | 0.41 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.39 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.38 |
| ▸ | PPOX | P50336 | 1/20 | 0.37 |
| ▸ | USP8 | P40818 | 1/20 | 0.35 |
| ▸ | USP7 | Q93009 | 1/20 | 0.35 |
| ▸ | CES1 | P23141 | 2/20 | 0.34 |
| ▸ | TGM2 | P21980 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9713833 | 0.83 | SOAT1 (0.61) | MAP2K7ELANECDC25ACDC25BS100A4 | |
| SCHEMBL10503268 | 0.76 | S100A4 (0.55) | MAP2K7CDC25ACDC25BS100A4HSP90AA1 | |
| SCHEMBL9713728 | 0.75 | S100A4 (0.49) | MAP2K7ELANECDC25ACDC25BS100A4 | |
| SCHEMBL9627970 | 0.74 | ALDH1A1 (0.57) | MAP2K7CDC25ACDC25BS100A4HSP90AA1 | |
| SCHEMBL9628282 | 0.73 | IDO1 (0.61) | CDC25ACDC25BS100A4HSP90AA1PTPN1 | |
| SCHEMBL30003034 | 0.73 | IDO1 (0.61) | CDC25ACDC25BS100A4HSP90AA1PTPN1 | |
| SCHEMBL8773066 | 0.73 | S100A4 (0.56) | S100A4HSP90AA1PTPN1PTPN11PPOX | |
| SCHEMBL9713414 | 0.73 | SOAT1 (0.69) | MAP2K7CDC25ACDC25BS100A4SOAT1 | |
| SCHEMBL9713379 | 0.71 | S100A4 (0.44) | CDC25ACDC25BS100A4HSP90AA1PTPN1 | |
| SCHEMBL23271777 | 0.70 | S100A4 (0.52) | S100A4HSP90AA1PTPN1PTPN11PPOX |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5091558-A | Topical administeration | SYNTEX (U.S.A.) INC. (US) | 1992-02-25 | — | — | US | disclosed |
| EP-0150831-B1 | NAPHTHALENE ANTI-PSORIATIC AGENTS | SYNTEX (U.S.A.) INC. (US) | 1988-08-10 | — | — | EP | disclosed |