Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 4/20 | 0.40 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.38 |
| ▸ | LDHA | P00338 | 1/20 | 0.37 |
| ▸ | LDHB | P07195 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9627724 | 0.80 | ALOX5 (0.48) | GAAMAPTLDHALDHBHTT | |
| SCHEMBL29370930 | 0.79 | GAA (0.51) | GAAMAPTLMNAPOLBALDH1A1 | |
| SCHEMBL9627592 | 0.78 | ABCB11 (0.51) | GAAMAPTLMNAALDH1A1KMT2A | |
| SCHEMBL9627613 | 0.74 | KDM4E (0.46) | GAAMAPTALDH1A1KDM4EHPGD | |
| SCHEMBL9628428 | 0.74 | KDM4E (0.46) | GAAMAPTALDH1A1KMT2AKDM4E | |
| SCHEMBL9713327 | 0.74 | ABCB11 (0.40) | GAAMAPTLMNAALDH1A1KMT2A | |
| SCHEMBL9713474 | 0.73 | KMT2A (0.42) | GAAMAPTLMNAALDH1A1KMT2A | |
| SCHEMBL29371748 | 0.73 | KMT2A (0.53) | GAAMAPTLMNAPOLBALDH1A1 | |
| SCHEMBL9659069 | 0.73 | KDM4E (0.46) | LMNAALDH1A1KDM4EHPGD | |
| SCHEMBL9627497 | 0.73 | ALOX5 (0.48) | GAAMAPTALDH1A1KDM4EHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5091558-A | Topical administeration | SYNTEX (U.S.A.) INC. (US) | 1992-02-25 | — | — | US | disclosed |
| EP-0150831-B1 | NAPHTHALENE ANTI-PSORIATIC AGENTS | SYNTEX (U.S.A.) INC. (US) | 1988-08-10 | — | — | EP | disclosed |
| EP-0150831-A2 | Naphthalene anti-psoriatic agents | SYNTEX (U.S.A.) INC. (US) | 1985-08-07 | — | — | EP | disclosed |