Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | TOP1 | P11387 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.38 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.38 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.38 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.38 |
| ▸ | KDR | P35968 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | MTNR1A | P48039 | 3/20 | 0.38 |
| ▸ | MTNR1B | P49286 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | BRAF | P15056 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9713113 | 0.87 | HTT (0.42) | MAPTALDH1A1MEN1KMT2APOLB | |
| SCHEMBL9713601 | 0.86 | TUBB4A (0.38) | MAPTALDH1A1MEN1KMT2APOLB | |
| SCHEMBL10892237 | 0.85 | KDM4E (0.41) | MAPTALDH1A1MEN1KMT2APOLB | |
| SCHEMBL9713973 | 0.81 | ABCB11 (0.41) | MAPTALDH1A1MEN1KMT2AHPGD | |
| SCHEMBL9713640 | 0.78 | ALDH1A1 (0.38) | MAPTALDH1A1MEN1KMT2APOLB | |
| SCHEMBL9713440 | 0.78 | HTT (0.40) | MAPTALDH1A1MEN1KMT2APOLB | |
| SCHEMBL9627528 | 0.75 | HTT (0.48) | MAPTALDH1A1TOP1MEN1KMT2A | |
| SCHEMBL9660612 | 0.73 | HTT (0.52) | MAPTALDH1A1TOP1MEN1KMT2A | |
| SCHEMBL9629327 | 0.72 | HTT (0.44) | MAPTALDH1A1MEN1KMT2APOLB | |
| SCHEMBL9644096 | 0.70 | ABCB11 (0.42) | MAPTALDH1A1MEN1KMT2AHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5091558-A | Topical administeration | SYNTEX (U.S.A.) INC. (US) | 1992-02-25 | — | — | US | disclosed |
| EP-0150831-B1 | NAPHTHALENE ANTI-PSORIATIC AGENTS | SYNTEX (U.S.A.) INC. (US) | 1988-08-10 | — | — | EP | disclosed |
| EP-0150831-A2 | Naphthalene anti-psoriatic agents | SYNTEX (U.S.A.) INC. (US) | 1985-08-07 | — | — | EP | disclosed |