Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | TUBB4A | P04350 | 6/20 | 0.38 |
| ▸ | TUBB | P07437 | 6/20 | 0.38 |
| ▸ | TUBA3C | P0DPH7 | 6/20 | 0.38 |
| ▸ | TUBA1B | P68363 | 6/20 | 0.38 |
| ▸ | TUBA4A | P68366 | 6/20 | 0.38 |
| ▸ | TUBB4B | P68371 | 6/20 | 0.38 |
| ▸ | TUBB3 | Q13509 | 6/20 | 0.38 |
| ▸ | TUBB2A | Q13885 | 6/20 | 0.38 |
| ▸ | TUBB8 | Q3ZCM7 | 6/20 | 0.38 |
| ▸ | TUBA3E | Q6PEY2 | 6/20 | 0.38 |
| ▸ | TUBA1A | Q71U36 | 6/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9629327 | 0.85 | HTT (0.44) | ALDH1A1KMT2AGAAMAPTL3MBTL1 | |
| SCHEMBL9713973 | 0.84 | ABCB11 (0.41) | ALDH1A1KMT2AGAAMAPTL3MBTL1 | |
| SCHEMBL9713113 | 0.84 | HTT (0.42) | ALDH1A1KMT2AGAAMAPTL3MBTL1 | |
| SCHEMBL10832811 | 0.83 | ABCB11 (0.46) | ALDH1A1KMT2AGAAMAPTL3MBTL1 | |
| SCHEMBL9713440 | 0.82 | HTT (0.40) | ALDH1A1KMT2AGAAMAPTL3MBTL1 | |
| SCHEMBL9713601 | 0.81 | TUBB4A (0.38) | ALDH1A1KMT2AGAAMAPTL3MBTL1 | |
| SCHEMBL9627528 | 0.79 | HTT (0.48) | ALDH1A1KMT2AGAAMAPTL3MBTL1 | |
| SCHEMBL9713596 | 0.78 | MAPT (0.41) | ALDH1A1KMT2AMAPTL3MBTL1MEN1 | |
| SCHEMBL9660612 | 0.76 | HTT (0.52) | ALDH1A1KMT2AGAAMAPTL3MBTL1 | |
| SCHEMBL9713691 | 0.76 | KMT2A (0.36) | ALDH1A1KMT2AGAAMAPTL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5091558-A | Topical administeration | SYNTEX (U.S.A.) INC. (US) | 1992-02-25 | — | — | US | disclosed |
| EP-0150831-B1 | NAPHTHALENE ANTI-PSORIATIC AGENTS | SYNTEX (U.S.A.) INC. (US) | 1988-08-10 | — | — | EP | disclosed |
| EP-0150831-A2 | Naphthalene anti-psoriatic agents | SYNTEX (U.S.A.) INC. (US) | 1985-08-07 | — | — | EP | disclosed |