Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB11 | O95342 | 1/20 | 0.41 |
| ▸ | SLC6A9 | P48067 | 4/20 | 0.39 |
| ▸ | EGFR | P00533 | 1/20 | 0.39 |
| ▸ | LCK | P06239 | 1/20 | 0.39 |
| ▸ | RHEB | Q15382 | 1/20 | 0.37 |
| ▸ | DHFR | P00374 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9713113 | 0.89 | HTT (0.42) | DHFRALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL10832739 | 0.85 | ABCB11 (0.52) | ABCB11SLC6A9EGFRLCKRHEB | |
| SCHEMBL9713640 | 0.84 | ALDH1A1 (0.38) | ABCB11ALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL9713601 | 0.83 | TUBB4A (0.38) | SLC6A9DHFRALDH1A1MAPTMEN1 | |
| SCHEMBL9713596 | 0.81 | MAPT (0.41) | ALDH1A1MAPTMEN1KMT2AHPGD | |
| SCHEMBL9713440 | 0.80 | HTT (0.40) | ALDH1A1MAPTMEN1KMT2AHPGD | |
| SCHEMBL9629327 | 0.79 | HTT (0.44) | ABCB11ALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL9627528 | 0.77 | HTT (0.48) | ABCB11ALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL9660612 | 0.75 | HTT (0.52) | ABCB11ALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL9713953 | 0.75 | HTT (0.42) | ABCB11ALDH1A1MAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5091558-A | Topical administeration | SYNTEX (U.S.A.) INC. (US) | 1992-02-25 | — | — | US | disclosed |
| EP-0150831-B1 | NAPHTHALENE ANTI-PSORIATIC AGENTS | SYNTEX (U.S.A.) INC. (US) | 1988-08-10 | — | — | EP | disclosed |
| EP-0150831-A2 | Naphthalene anti-psoriatic agents | SYNTEX (U.S.A.) INC. (US) | 1985-08-07 | — | — | EP | disclosed |