Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 1/20 | 0.53 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.53 |
| ▸ | PPARG | P37231 | 5/20 | 0.48 |
| ▸ | PPARA | Q07869 | 5/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | ACACB | O00763 | 3/20 | 0.44 |
| ▸ | ACACA | Q13085 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | CRHBP | P24387 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9713748 | 1.00 | MTNR1A (0.53) | MTNR1AMTNR1BPPARGPPARAALDH1A1 | |
| SCHEMBL11752040 | 0.88 | MAPT (0.57) | MTNR1AMTNR1BPPARGPPARAMAPT | |
| SCHEMBL896832 | 0.88 | MTNR1A (0.53) | MTNR1AMTNR1BALDH1A1MAPTHPGD | |
| SCHEMBL896676 | 0.88 | MTNR1A (0.53) | MTNR1AMTNR1BALDH1A1MAPTHPGD | |
| SCHEMBL11753291 | 0.86 | LDHA (0.44) | MTNR1AMTNR1BPPARGPPARAALDH1A1 | |
| SCHEMBL11753613 | 0.86 | PPARG (0.45) | PPARGPPARAACACBACACA | |
| SCHEMBL11752042 | 0.86 | ALDH1A1 (0.44) | MTNR1AMTNR1BPPARGPPARAALDH1A1 | |
| Diphenylether SCHEMBL8825712 | 0.82 | LMNA (0.55) | MTNR1AMTNR1BALDH1A1ACACBACACA | |
| SCHEMBL4775744 | 0.81 | LDHA (0.47) | MTNR1AMTNR1BPPARGPPARAALDH1A1 | |
| SCHEMBL4775742 | 0.81 | LDHA (0.47) | MTNR1AMTNR1BPPARGPPARAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0246713-B1 | INTERMEDIATES FOR THE PRODUCTION OF NITROGEN-CONTAINING SUBSTITUTED HETEROCYCLIC COMPOUNDS | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1992-03-04 | — | — | EP | disclosed |
| EP-0246713-A2 | Intermediates for the production of nitrogen-containing substituted heterocyclic compounds | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1987-11-25 | — | — | EP | disclosed |