Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB11 | O95342 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | MAP2 | P11137 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.39 |
| ▸ | PPARG | P37231 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | BACE1 | P56817 | 1/20 | 0.39 |
| ▸ | PDE4A | P27815 | 1/20 | 0.39 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.39 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.39 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9713656 | 0.79 | ABCB11 (0.48) | ABCB11ALDH1A1MAP2MAPTHPGD | |
| SCHEMBL10502752 | 0.79 | PDE4A (0.40) | ABCB11ALDH1A1MAPTHPGDMEN1 | |
| SCHEMBL10503628 | 0.79 | ABCB11 (0.64) | ABCB11ALDH1A1MAP2MAPTHPGD | |
| SCHEMBL9713703 | 0.76 | ABCB11 (0.51) | ABCB11ALDH1A1MAPTHPGDMEN1 | |
| SCHEMBL27971141 | 0.71 | MAP2 (0.62) | ALDH1A1MAP2MAPTHPGDMEN1 | |
| SCHEMBL10503117 | 0.71 | KDM4E (0.49) | ALDH1A1MAPTHPGDMEN1TSHR | |
| SCHEMBL29371228 | 0.71 | ABCB11 (0.73) | ABCB11ALDH1A1MAP2MAPTHPGD | |
| SCHEMBL10503448 | 0.69 | MAPT (0.43) | ABCB11MAPTMEN1CYP3A4ALOX15 | |
| SCHEMBL10742406 | 0.69 | ABCB11 (0.48) | ABCB11MAP2MAPTHSD17B10BACE1 | |
| SCHEMBL9643184 | 0.68 | MRGPRX4 (0.42) | ABCB11ALDH1A1MAP2MAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5091558-A | Topical administeration | SYNTEX (U.S.A.) INC. (US) | 1992-02-25 | — | — | US | disclosed |
| EP-0150831-B1 | NAPHTHALENE ANTI-PSORIATIC AGENTS | SYNTEX (U.S.A.) INC. (US) | 1988-08-10 | — | — | EP | disclosed |
| EP-0150831-A2 | Naphthalene anti-psoriatic agents | SYNTEX (U.S.A.) INC. (US) | 1985-08-07 | — | — | EP | disclosed |