Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB11 | O95342 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 5/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.41 |
| ▸ | PDE7B | Q9NP56 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | TP53 | P04637 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | RHEB | Q15382 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9713437 | 0.84 | PDE7A (0.40) | ABCB11MAPTMEN1KMT2ALMNA | |
| SCHEMBL9713684 | 0.83 | ABCB11 (0.57) | ABCB11HTTMAPTKDM4EMEN1 | |
| SCHEMBL30226594 | 0.83 | ABCB11 (0.43) | ABCB11MAPTMEN1KMT2ALMNA | |
| SCHEMBL30226615 | 0.82 | PDE7A (0.39) | ABCB11MAPTMEN1KMT2ALMNA | |
| SCHEMBL9713758 | 0.81 | L3MBTL1 (0.48) | MAPTMEN1KMT2ALMNAHPGD | |
| SCHEMBL30226778 | 0.81 | HTT (0.49) | HTTMAPTKDM4EMEN1KMT2A | |
| SCHEMBL9713468 | 0.80 | ABCB11 (0.53) | ABCB11HTTMAPTKDM4EMEN1 | |
| SCHEMBL9713245 | 0.78 | ABCB11 (0.53) | ABCB11HTTMAPTKDM4EMEN1 | |
| SCHEMBL9713764 | 0.76 | ABCB11 (0.46) | ABCB11MAPTMEN1KMT2AHPGD | |
| SCHEMBL29371228 | 0.75 | ABCB11 (0.73) | ABCB11HTTMAPTKDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5091558-A | Topical administeration | SYNTEX (U.S.A.) INC. (US) | 1992-02-25 | — | — | US | disclosed |
| EP-0150831-B1 | NAPHTHALENE ANTI-PSORIATIC AGENTS | SYNTEX (U.S.A.) INC. (US) | 1988-08-10 | — | — | EP | disclosed |
| EP-0150831-A2 | Naphthalene anti-psoriatic agents | SYNTEX (U.S.A.) INC. (US) | 1985-08-07 | — | — | EP | disclosed |