Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | IGLV6-57 | P01721 | 1/20 | 0.42 |
| ▸ | TUBB4A | P04350 | 2/20 | 0.41 |
| ▸ | TUBB | P07437 | 2/20 | 0.41 |
| ▸ | TUBA3C | P0DPH7 | 2/20 | 0.41 |
| ▸ | TUBA1B | P68363 | 2/20 | 0.41 |
| ▸ | TUBA4A | P68366 | 2/20 | 0.41 |
| ▸ | TUBB4B | P68371 | 2/20 | 0.41 |
| ▸ | TUBB3 | Q13509 | 2/20 | 0.41 |
| ▸ | TUBB2A | Q13885 | 2/20 | 0.41 |
| ▸ | TUBB8 | Q3ZCM7 | 2/20 | 0.41 |
| ▸ | TUBA3E | Q6PEY2 | 2/20 | 0.41 |
| ▸ | TUBA1A | Q71U36 | 2/20 | 0.41 |
| ▸ | TUBA1C | Q9BQE3 | 2/20 | 0.41 |
| ▸ | TUBB6 | Q9BUF5 | 2/20 | 0.41 |
| ▸ | TUBB2B | Q9BVA1 | 2/20 | 0.41 |
| ▸ | TUBB1 | Q9H4B7 | 2/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.41 |
| ▸ | BACE1 | P56817 | 2/20 | 0.40 |
| ▸ | LTB4R | Q15722 | 4/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9641905 | 0.85 | ABCB11 (0.53) | IGLV6-57FFAR1BACE1LTB4RLTB4R2 | |
| SCHEMBL9627729 | 0.82 | TUBB4A (0.54) | HTTTUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL9643306 | 0.81 | ABCB11 (0.46) | HTTIGLV6-57FFAR1BACE1LTB4R | |
| SCHEMBL9643227 | 0.79 | ABCB11 (0.46) | IGLV6-57FFAR1BACE1LTB4RLTB4R2 | |
| SCHEMBL9627386 | 0.79 | HTT (0.48) | HTTTUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL9627465 | 0.78 | HTT (0.69) | HTTTUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL9627366 | 0.78 | HTT (0.50) | HTTTUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL9713775 | 0.77 | ALOX5 (0.51) | HTTFFAR1ALOX5MEN1KMT2A | |
| SCHEMBL9628112 | 0.77 | TUBB4A (0.45) | HTTTUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL9643340 | 0.76 | ABCB11 (0.43) | IGLV6-57FFAR1LTB4RLTB4R2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5091558-A | Topical administeration | SYNTEX (U.S.A.) INC. (US) | 1992-02-25 | — | — | US | disclosed |
| EP-0150831-B1 | NAPHTHALENE ANTI-PSORIATIC AGENTS | SYNTEX (U.S.A.) INC. (US) | 1988-08-10 | — | — | EP | disclosed |
| EP-0150831-A2 | Naphthalene anti-psoriatic agents | SYNTEX (U.S.A.) INC. (US) | 1985-08-07 | — | — | EP | disclosed |