Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 3/20 | 0.51 |
| ▸ | ACHE | P22303 | 1/20 | 0.46 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.44 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.44 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | SLC16A3 | O15427 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9641912 | 0.86 | ABCB11 (0.51) | ALOX5ACHEMTNR1AMTNR1BMEN1 | |
| SCHEMBL9643309 | 0.82 | ABCB11 (0.44) | ALOX5ACHEMTNR1AMTNR1BMEN1 | |
| SCHEMBL9628112 | 0.82 | TUBB4A (0.45) | ALOX5MEN1KMT2AHTT | |
| SCHEMBL9642419 | 0.81 | ALOX5 (0.46) | ALOX5ACHEMTNR1AMTNR1BMEN1 | |
| SCHEMBL9642538 | 0.81 | ALOX5 (0.46) | ALOX5ACHEMTNR1AMTNR1BMEN1 | |
| SCHEMBL9627729 | 0.80 | TUBB4A (0.54) | ALOX5MEN1KMT2AHTT | |
| SCHEMBL9627895 | 0.80 | CFD (0.47) | ALOX5PTGS2HTT | |
| SCHEMBL9643230 | 0.80 | ABCB11 (0.44) | ALOX5ACHEMTNR1AMTNR1BMEN1 | |
| SCHEMBL9713770 | 0.77 | HTT (0.44) | ALOX5MEN1KMT2AFFAR1HTT | |
| SCHEMBL9643346 | 0.77 | SLC2A4 (0.43) | ALOX5ACHEMTNR1AMTNR1BMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5091558-A | Topical administeration | SYNTEX (U.S.A.) INC. (US) | 1992-02-25 | — | — | US | disclosed |
| EP-0150831-B1 | NAPHTHALENE ANTI-PSORIATIC AGENTS | SYNTEX (U.S.A.) INC. (US) | 1988-08-10 | — | — | EP | disclosed |
| EP-0150831-A2 | Naphthalene anti-psoriatic agents | SYNTEX (U.S.A.) INC. (US) | 1985-08-07 | — | — | EP | disclosed |