Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 3/20 | 0.53 |
| ▸ | PKM | P14618 | 2/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | IDO1 | P14902 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | CA1 | P00915 | 3/20 | 0.47 |
| ▸ | CA2 | P00918 | 3/20 | 0.47 |
| ▸ | CA12 | O43570 | 2/20 | 0.47 |
| ▸ | CA9 | Q16790 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | MMP1 | P03956 | 1/20 | 0.46 |
| ▸ | MMP2 | P08253 | 1/20 | 0.46 |
| ▸ | MMP9 | P14780 | 1/20 | 0.46 |
| ▸ | MMP8 | P22894 | 1/20 | 0.46 |
| ▸ | MMP13 | P45452 | 1/20 | 0.46 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9713818 | 0.86 | PKM (0.63) | GAAPKMCYP2C19ALDH1A1L3MBTL1 | |
| SCHEMBL9713937 | 0.83 | KMT2A (0.66) | GAAPKMALDH1A1KMT2ALMNA | |
| SCHEMBL9713845 | 0.77 | HTR6 (0.46) | PKMCYP2C19ALDH1A1TSHRKMT2A | |
| Acedapsone SCHEMBL152710 | 0.74 | PKM (0.85) | GAAPKMCYP2C19ALDH1A1L3MBTL1 | |
| SCHEMBL59093 | 0.74 | SMN1; SMN2 (0.61) | GAACYP2C19ALDH1A1L3MBTL1TSHR | |
| SCHEMBL9714044 | 0.73 | ALDH1A1 (0.59) | GAAPKMALDH1A1L3MBTL1TSHR | |
| Acedapsone SCHEMBL28716352 | 0.73 | PKM (0.82) | GAAPKMCYP2C19ALDH1A1L3MBTL1 | |
| Acedapsone SCHEMBL22518385 | 0.73 | PKM (0.82) | GAAPKMCYP2C19ALDH1A1L3MBTL1 | |
| Acedapsone SCHEMBL28254874 | 0.70 | PKM (0.72) | GAAPKMCYP2C19ALDH1A1L3MBTL1 | |
| SCHEMBL9713935 | 0.69 | PKM (0.67) | GAAPKMCYP2C19ALDH1A1IDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5084449-A | Bactericides and antiprotozoa agents | DR. KARL THOMAE GMBH (DE) | 1992-01-28 | — | — | US | disclosed |
| US-4992430-A | Anti-bacterial compositions comprising a substituted bis-(4-aminophenyl)-sulfone and a dihydro-folic acid reductase | DR. KARL THOMAE GMBH (DE) | 1991-02-12 | — | — | US | disclosed |
| US-4829058-A | INHIBITORS OF BACTERIA, MYCOBACTERIA AND PLASMODIA | DR. KARL THOMAE GMBH (DE) | 1989-05-09 | — | — | US | disclosed |