Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 7/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | MPO | P05164 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.39 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.37 |
| ▸ | CA12 | O43570 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9713990 | 0.89 | HTR6 (0.50) | HTR6ALDH1A1CYP3A4TDP1LMNA | |
| SCHEMBL9713635 | 0.84 | ALDH1A1 (0.46) | HTR6ALDH1A1CYP3A4ALOX15TP53 | |
| SCHEMBL9713941 | 0.80 | ALDH1A1 (0.46) | HTR6ALDH1A1CYP3A4ALOX15TDP1 | |
| SCHEMBL17774674 | 0.79 | HTR6 (0.50) | HTR6ALDH1A1CYP3A4TDP1LMNA | |
| SCHEMBL9713804 | 0.77 | GAA (0.53) | ALDH1A1LMNATSHRPKMMEN1 | |
| SCHEMBL30543085 | 0.74 | HTR6 (0.53) | HTR6ALDH1A1CYP3A4ALOX15TP53 | |
| SCHEMBL21378334 | 0.74 | HTR6 (0.53) | HTR6ALDH1A1CYP3A4ALOX15TP53 | |
| SCHEMBL9713818 | 0.74 | PKM (0.63) | ALDH1A1LMNATSHRPKMMEN1 | |
| SCHEMBL17774692 | 0.72 | HTR6 (0.46) | HTR6ALDH1A1CYP3A4TDP1LMNA | |
| SCHEMBL16638466 | 0.71 | CA12 (0.68) | HTR6ALDH1A1CYP3A4ALOX15TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5084449-A | Bactericides and antiprotozoa agents | DR. KARL THOMAE GMBH (DE) | 1992-01-28 | — | — | US | disclosed |
| US-4992430-A | Anti-bacterial compositions comprising a substituted bis-(4-aminophenyl)-sulfone and a dihydro-folic acid reductase | DR. KARL THOMAE GMBH (DE) | 1991-02-12 | — | — | US | disclosed |
| US-4829058-A | INHIBITORS OF BACTERIA, MYCOBACTERIA AND PLASMODIA | DR. KARL THOMAE GMBH (DE) | 1989-05-09 | — | — | US | disclosed |