Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 16/20 | 0.58 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | PKM | P14618 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10831598 | 0.84 | ABCB11 (0.54) | PTGS2ABCB11LMNAPKMHTT | |
| SCHEMBL9713684 | 0.80 | ABCB11 (0.57) | PTGS2ABCB11LMNAHTTNPC1 | |
| SCHEMBL9713395 | 0.78 | ABCB11 (0.52) | PTGS2ABCB11HTTNPC1RAB9A | |
| SCHEMBL9713468 | 0.76 | ABCB11 (0.53) | PTGS2ABCB11LMNAHTTNPC1 | |
| SCHEMBL9713703 | 0.74 | ABCB11 (0.51) | PTGS2ABCB11LMNAHTTNPC1 | |
| SCHEMBL6535129 | 0.74 | PTGS2 (1.00) | PTGS2 | |
| SCHEMBL9628176 | 0.73 | ABCB11 (0.56) | PTGS2ABCB11LMNAHTTHPGD | |
| SCHEMBL13659627 | 0.73 | PTGS2 (1.00) | PTGS2 | |
| SCHEMBL9643195 | 0.72 | ABCB11 (0.58) | PTGS2ABCB11ALOX5 | |
| SCHEMBL9642724 | 0.72 | ABCB11 (0.58) | PTGS2ABCB11ALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5091558-A | Topical administeration | SYNTEX (U.S.A.) INC. (US) | 1992-02-25 | — | — | US | disclosed |
| EP-0150831-B1 | NAPHTHALENE ANTI-PSORIATIC AGENTS | SYNTEX (U.S.A.) INC. (US) | 1988-08-10 | — | — | EP | disclosed |
| EP-0150831-A2 | Naphthalene anti-psoriatic agents | SYNTEX (U.S.A.) INC. (US) | 1985-08-07 | — | — | EP | disclosed |