Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB11 | O95342 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 4/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 5/20 | 0.33 |
| ▸ | TOP1 | P11387 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
| ▸ | HTR2B | P41595 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9713684 | 0.85 | ABCB11 (0.57) | ABCB11HTTMAPTKDM4EMEN1 | |
| SCHEMBL10832118 | 0.81 | ABCB11 (0.62) | ABCB11HTTMAPTKDM4EMEN1 | |
| SCHEMBL9713703 | 0.80 | ABCB11 (0.51) | ABCB11HTTMAPTKDM4EMEN1 | |
| SCHEMBL9629306 | 0.77 | ABCB11 (0.68) | ABCB11HTTMAPTKDM4EMEN1 | |
| SCHEMBL9714031 | 0.76 | PTGS2 (0.58) | ABCB11HTTLMNAHPGDNPSR1 | |
| SCHEMBL9713401 | 0.75 | ABCB11 (0.51) | ABCB11HTTMAPTKDM4EMEN1 | |
| SCHEMBL9713667 | 0.75 | ABCB11 (0.65) | ABCB11HTTMAPTKDM4EMEN1 | |
| SCHEMBL9627379 | 0.74 | ABCB11 (0.68) | ABCB11HTTMAPTKDM4EMEN1 | |
| SCHEMBL9713732 | 0.74 | ABCB11 (0.56) | ABCB11HTTMAPTKDM4EMEN1 | |
| SCHEMBL9628176 | 0.74 | ABCB11 (0.56) | ABCB11HTTMAPTKDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5091558-A | Topical administeration | SYNTEX (U.S.A.) INC. (US) | 1992-02-25 | — | — | US | disclosed |
| EP-0150831-B1 | NAPHTHALENE ANTI-PSORIATIC AGENTS | SYNTEX (U.S.A.) INC. (US) | 1988-08-10 | — | — | EP | disclosed |
| EP-0150831-A2 | Naphthalene anti-psoriatic agents | SYNTEX (U.S.A.) INC. (US) | 1985-08-07 | — | — | EP | disclosed |