Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 11/20 | 0.46 |
| ▸ | MMP9 | P14780 | 9/20 | 0.46 |
| ▸ | MMP8 | P22894 | 8/20 | 0.46 |
| ▸ | MMP1 | P03956 | 7/20 | 0.39 |
| ▸ | MMP3 | P08254 | 5/20 | 0.36 |
| ▸ | ADAM17 | P78536 | 2/20 | 0.36 |
| ▸ | MMP13 | P45452 | 1/20 | 0.36 |
| ▸ | MMP14 | P50281 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6435813 | 0.72 | MMP2 (0.48) | MMP2MMP9MMP8MMP1MMP3 | |
| SCHEMBL9713776 | 0.65 | ALDH1A1 (0.64) | SMN1; SMN2ALDH1A1 | |
| SCHEMBL8252118 | 0.63 | TP53 (0.79) | SMN1; SMN2ALDH1A1TP53 | |
| SCHEMBL17152630 | 0.63 | ALDH1A1 (0.64) | SMN1; SMN2ALDH1A1 | |
| SCHEMBL12310326 | 0.62 | TSHR (0.58) | SMN1; SMN2ALDH1A1 | |
| SCHEMBL17211991 | 0.62 | SMN1; SMN2 (0.43) | SMN1; SMN2ALDH1A1 | |
| SCHEMBL12310697 | 0.62 | TSHR (0.58) | SMN1; SMN2ALDH1A1 | |
| SCHEMBL16148125 | 0.62 | TSHR (0.58) | SMN1; SMN2ALDH1A1 | |
| SCHEMBL9868632 | 0.62 | MMP3 (0.45) | MMP9MMP1MMP3SMN1; SMN2ALDH1A1 | |
| SCHEMBL9868641 | 0.62 | MMP3 (0.45) | MMP9MMP1MMP3SMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0497192-A2 | Amino acid derivatives | F. HOFFMANN-LA ROCHE AG (CH) | 1992-08-05 | — | — | EP | disclosed |